This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants. |
References |
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1.J Immunol. 2019 Mar 1;202(5):1428-1440. 2.Am J Hum Genet. 2020 Oct 1;107(4):753-762. |
Specification | |
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Aliases | LMN;ADLD;LMN2; LMNB;MCPH26 |
Entrez GeneID | 4001 |
Swissprot | P20700 |
clone | 2A11A2 |
WB Predicted band size | 66.4kDa |
Host/Isotype | Mouse IgG1 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human LMNB1 (AA: 413-583) expressed in HEK293-6e cells supernatant. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |