产品展厅
产品展厅
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The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. |
| References |
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1.Cancer Sci. 2015 Sep;106(9):1224-31. 2.J Hypertens. 2013 Dec;31(12):2362-9. |
| Specification | |
|---|---|
| Aliases | P2X7 |
| Entrez GeneID | 5027 |
| Swissprot | Q99572 |
| clone | 7G1D6 |
| WB Predicted band size | 68.6kDa |
| Host/Isotype | Mouse IgG2b |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human P2RX7 (AA: 226-452) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
