The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. |
References |
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1. PLoS One. 2012;7(7):e41160. 2. J Biol Chem. 2011 Feb 18;286(7):5375-82. |
Specification | |
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Aliases | GS2; RAM; RAB27; HsT18676 |
Entrez GeneID | 5873 |
Swissprot | P51159 |
clone | 7D7C9 |
WB Predicted band size | 24.9kDa |
Host/Isotype | Mouse IgG2b |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human RAB27A (AA: FULL(1-221)) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |