产品展厅
产品展厅
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This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). |
| References |
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1.J Biol Chem. 2011 May 13;286(19):16541-5. 2.PLoS One. 2010 Dec 20;5(12):e15560. |
| Specification | |
|---|---|
| Aliases | GLUT4 |
| Entrez GeneID | 6517 |
| Swissprot | P14672 |
| clone | 3G10A3 |
| WB Predicted band size | 54.8kDa |
| Host/Isotype | Mouse IgG2b |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Purified recombinant fragment of human SLC2A4 (AA: 224-353 ) expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
