| Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. |
| References |
|---|
|
1. Pediatr Allergy Immunol. 2010 Dec;21(8):1151-6. 2. J Biol Chem. 2010 Dec 31;285(53):41422-31. |
| Specification | |
|---|---|
| Aliases | NOS; INOS; NOS2A; HEP-NOS |
| Entrez GeneID | 4843 |
| Swissprot | P35228 |
| clone | 4E5 |
| WB Predicted band size | 131kDa |
| Host/Isotype | Mouse IgG1 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen |
Purified recombinant fragment of human NOS2 expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |