Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. |
References |
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1. Pediatr Allergy Immunol. 2010 Dec;21(8):1151-6. 2. J Biol Chem. 2010 Dec 31;285(53):41422-31. |
Specification | |
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Aliases | NOS; INOS; NOS2A; HEP-NOS |
Entrez GeneID | 4843 |
Swissprot | P35228 |
clone | 4E5 |
WB Predicted band size | 131kDa |
Host/Isotype | Mouse IgG1 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen |
Purified recombinant fragment of human NOS2 expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |