产品展厅
产品展厅
| This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| References |
|---|
|
1. Biol Pharm Bull. 2009 Apr;32(4):573-7. 2. Clin Chim Acta. 2009 Apr;402(1-2):189-92. |
| Specification | |
|---|---|
| Aliases | PAI; PAI1; PAI-1; PLANH1 |
| Entrez GeneID | 5054 |
| Swissprot | P05121 |
| clone | 1D5 |
| WB Predicted band size | 45kDa |
| Host/Isotype | Mouse IgG1 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen |
Purified recombinant fragment of human SERPINE1 expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
