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Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue; in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome. |
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1. Cancer Res. 2013 Jan 15;73(2):662-71. 2. Cancer Res. 2012 Dec 15;72(24):6382-92. |
| Specification | |
|---|---|
| Aliases | SCS; ACS3; CRS1; BPES2; BPES3; TWIST; bHLHa38 |
| Entrez GeneID | 7291 |
| Swissprot | Q15672 |
| clone | 10E4E6 |
| WB Predicted band size | 21kDa |
| Host/Isotype | Mouse IgG1 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Purified recombinant fragment of human TWIST1 (AA: 9-74) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |