产品展厅
产品展厅
| This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. |
| References |
|---|
|
1. J Biol Chem. 2010 Jun 11;285(24):18276-82. 2. Scand J Immunol. 2009 Sep;70(3):264-76. |
| Specification | |
|---|---|
| Aliases | IPD1; REN64; NY-REN-64 |
| Entrez GeneID | 51135 |
| Swissprot | Q9NWZ3 |
| clone | 2H9 |
| WB Predicted band size | 52kDa |
| Host/Isotype | Mouse IgG1 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Monkey |
| Immunogen |
Purified recombinant fragment of human IRAK4 expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
