This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. |
References |
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1. J Biol Chem. 2010 Mar 12;285(11):8218-26. 2. Mol Cancer. 2010 May 19;9:111. |
Specification | |
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Aliases | AP1; AP-1; c-Jun; Jun |
Entrez GeneID | 3725 |
Swissprot | P05412 |
clone | 5B1 |
WB Predicted band size | 43kDa |
Host/Isotype | Mouse IgG1 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Monkey |
Immunogen |
Purified recombinant fragment of human c-Jun expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |