产品展厅
产品展厅
| This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. |
| References |
|---|
|
1. Int J Cancer. 2009 Feb 1;124(3):664-9. 2. Reprod Sci. 2008 Dec;15(10):1018-26. |
| Specification | |
|---|---|
| Aliases | ENG; END; ORW; HHT1; ORW1; CD105; FLJ41744 |
| Entrez GeneID | 2022 |
| Swissprot | P17813 |
| clone | 3A9 |
| WB Predicted band size | 71kDa |
| Host/Isotype | Mouse IgG1 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen |
Purified recombinant fragment of human CD105 expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
