产品展厅
产品展厅
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This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. |
| References |
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1. BMC Cancer. 2012 Oct 30;12:501. 2. Am J Surg Pathol. 2012 Dec;36(12):1809-16. |
| Specification | |
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| Aliases | ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1 |
| Entrez GeneID | 4072 |
| Swissprot | P16422 |
| clone | 7B5C10 |
| WB Predicted band size | 35kDa |
| Host/Isotype | Mouse IgG1 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human EPCAM (AA: 24-265) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
