中文名
|
5-氨基水杨酸
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中文同义
|
5-氨基水杨酸;5-胺柳酸;美沙拉嗪;氨基水扬酸;5-氨基水杨酸(美沙拉秦);马拉沙嗪;5-氨基-2-羟基苯甲酸;氨水杨酸;美沙拉嗪
|
英文名
|
5-Aminosalicylic acid
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英文同义
|
5-Aminosalicylic acid, 98.5%, IKK inhibitor;2-HYDROXY-5-AMINOBENZOIC ACID;3-Carboxy-4-hydroxyaniline;5-AMINO-2-HYDROXYBENZOIC ACID;5-AMINOSALICYLIC ACID;5-ASA;5-AS;rowasa
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CAS
|
89-57-6
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分子式
|
C7H7NO3
|
分子量
|
153.14
|
EINECS
|
201-919-1
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结构式
|
|
性质
|
熔点
|
275-280 °C (dec.)(lit.)
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沸点
|
276.03°C (rough estimate)
|
密度
|
1.3585 (rough estimate)
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折射率
|
1.5500 (estimate)
|
闪点
|
279-281°C
|
储存条件
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2-8°C
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溶解度
|
Soluble in dimethyl sulfoxide.
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形态
|
tablets
|
酸度系数(pKa)
|
2.74, 5.84(at 25℃)
|
颜色
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off-white to gray
|
PH值
|
4.0-4.1 (0.8g/l, H2O, 20℃)
|
酸碱指示剂变色ph值范围
|
Non-B uorescence (3.1) to light green B uorescence (4.4)
|
水溶解性
|
<0.1 g/100 mL at 21 oC
|
Decomposition
|
279-281 oC
|
Merck
|
14,5904
|
BRN
|
2090421
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稳定性
|
Stable. Incompatible with acids, acid anhydrides, acid chlorides, chloroformates, strong oxidizing agents.
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主要应用
|
Detergent, hair dyes, prevention of colorectal cancer, treating inflammatory bowel disease, autoimmune disorders, gastrointestinal inflammation, chemokine-mediated diseases, mucosal tissue disorder, sleep disorders, rectoanal tenesmus, ulcerative colitis
|
InChIKey
|
KBOPZPXVLCULAV-UHFFFAOYSA-N
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NIST化学物质信息
|
Mesalamine(89-57-6)
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EPA化学物质信息
|
Benzoic acid, 5-amino-2-hydroxy- (89-57-6)
|